Item 2. PROPERTIES

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Item 2. PROPERTIES

As of December 31, 2020, we owned or leased approximately 180 properties. The locations and primary functions of significant properties are summarized in the following tables:


U.S. Location:	Manufacturing	Administrative	R&D	Sales & marketing	Warehouse	Distribution center
Thousand Oaks, CA*	P	P	P	P	P	P
San Francisco, CA			P
Louisville, KY					P	P
Cambridge, MA			P
Woburn, MA	P				P
Juncos, Puerto Rico	P	P			P	P
West Greenwich, RI	P	P			P
Tampa, FL		P
Other U.S. cities		P		P

Corporate headquarters


Ex-U.S. Location:	Manufacturing	Administrative	R&D	Sales & marketing	Warehouse	Distribution center
Brazil	P	P		P	P	P
Canada		P	P	P
China		P		P
Germany		P	P	P
Iceland		P	P
Ireland	P	P		P	P
Japan		P	P	P
Netherlands	P	P		P	P	P
Singapore	P	P		P	P
Switzerland		P		P
Turkey	P	P		P	P	P
United Kingdom		P	P	P
Other countries		P	P	P	P

Excluded from the information above are (i) undeveloped land and leased properties that have been abandoned and (ii) certain buildings we still own but that are no longer used in our business. There are no material encumbrances on our owned properties.

We believe our facilities are suitable for their intended uses and, in conjunction with our third-party contract manufacturing agreements, provide adequate capacity and are sufficient to meet our expected needs. See Item 1A. Risk Factors for a discussion of the factors that could adversely impact our manufacturing operations and the global supply of our products.

See Item 1. Business—Manufacturing, Distribution and Raw Materials.

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