A Dark Vector Cognition product

Item 2. PROPERTIES

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Item 2. PROPERTIES

General

As of December 31, 2024, we had 391 properties in North America consisting of approximately 44.1 million RSF of operating

properties and new Class A/A+ development and redevelopment properties under construction, including 67 properties that are held by

consolidated real estate joint ventures and four properties that are held by unconsolidated real estate joint ventures. The occupancy

percentage of our operating properties in North America was 94.6% as of December 31, 2024. The exteriors of our properties typically

resemble traditional office properties, but the interior infrastructures are designed to accommodate the needs of life science tenants.

These improvements typically are generic rather than specific to a particular tenant. As a result, we believe that the improvements have

long-term value and utility and are usable by a wide range of tenants. Improvements to our properties typically include:

  • Reinforced concrete floors;

  • Upgraded roof loading capacity;

  • Increased floor-to-ceiling heights;

  • Heavy-duty HVAC systems;

  • Enhanced environmental control technology;

  • Significantly upgraded electrical, gas, and plumbing infrastructure; and

  • Laboratory benches.

As of December 31, 2024, we held a fee simple interest in each of our properties, with the exception of 32 properties in North

America subject to ground leasehold interests, which accounted for approximately 8% of our total number of properties. Of these 32

properties, we held eight properties in the Greater Boston market, 20 properties in the San Francisco Bay Area market, one property in

the Seattle market, one property in the Maryland market, and two properties in the New York City market. During the year ended

December 31, 2024, as a percentage of net operating income our ground lease rental expense aggregated 1.6%. Refer to our

consolidated financial statements and notes thereto in “Item 15. Exhibits and financial statement schedules” in this annual report on

Form 10-K for further discussion.

As of December 31, 2024, we had over 1,000 leases with a total of approximately 800 tenants, and 171, or 44%, of our 391

properties were single-tenant properties. Leases in our multi-tenant buildings typically have initial terms of 3 to 9 years, while leases in

our single-tenant buildings typically have initial terms of 5 to 15 years. Additionally, as of December 31, 2024:

  • Investment-grade or publicly traded large cap tenants represented 52% of our total annual rental revenue;

  • Approximately 97% of our leases (on an annual rental revenue basis) contained effective annual rent escalations

approximating 3% that were either fixed or indexed based on a consumer price index or other index;

  • Approximately 92% of our leases (on an annual rental revenue basis) were triple net leases, which require tenants to pay

substantially all real estate taxes, insurance, utilities, repairs and maintenance, common area expenses, and other

operating expenses (including increases thereto) in addition to base rent;

  • Approximately 92% of our leases (on an annual rental revenue basis) provided for the recapture of capital expenditures

(such as HVAC maintenance and/or replacement, roof replacement, and parking lot resurfacing) that we believe would

typically be borne by the landlord in traditional office leases; and

  • 84% of our leasing activity during the last twelve months was generated from our existing tenant base.

Our leases also typically give us the right to review and approve tenant alterations to the property. Generally, tenant-installed

improvements to the properties are reusable generic improvements and remain our property after termination of the lease at our

election. However, we are permitted under the terms of most of our leases to require that the tenant, at its expense, remove certain

non-generic improvements and restore the premises to their original condition.

Refer to “Annual rental revenue” and “Operating statistics” under “Definitions and reconciliations” in Item 7 in this annual report

on Form 10-K for a description of the basis used to compute the aforementioned measures.

Locations of properties

Our properties are strategically located in AAA life science innovation cluster markets. The following table sets forth the total

RSF, number of properties, and annual rental revenue in effect as of December 31, 2024 in each of our markets in North America

(dollars in thousands, except per RSF amounts):

RSFNumber of PropertiesAnnual Rental Revenue
MarketOperatingDevelopmentRedevelopmentTotal% of TotalTotal% of TotalPer RSF
Greater Boston9,260,235632,8501,601,01011,494,09526%64$760,56436%$86.67
San Francisco Bay Area7,680,005394,781366,9398,441,7251965443,3452166.78
San Diego7,382,450921,510—8,303,9601979326,9251645.97
Seattle3,186,812227,577—3,414,389845136,014546.19
Maryland3,849,928——3,849,928950144,032739.53
Research Triangle3,802,204——3,802,204938116,808631.53
New York City921,774——921,7742473,534490.26
Texas1,845,159—73,2981,918,45741544,022224.99
Canada888,189—139,3111,027,50021119,661123.08
Non-cluster/other markets349,099——349,09911015,027159.35
Properties held for sale600,870——600,87011013,0561N/A
North America39,766,7252,176,7182,180,55844,124,001100%391$2,092,988100%$56.98
4,357,276

Summary of occupancy percentages in North America

The following table sets forth the occupancy percentages for our operating properties and our operating and redevelopment

properties in each of our North America markets, excluding properties held for sale, as of the following dates:

Operating PropertiesOperating and Redevelopment Properties
Market12/31/2412/31/2312/31/2212/31/2412/31/2312/31/22
Greater Boston94.8%94.9%94.5%80.8%84.7%85.5%
San Francisco Bay Area93.394.896.789.191.493.3
San Diego96.394.195.496.394.195.4
Seattle92.495.297.092.490.790.1
Maryland95.795.695.895.795.693.3
Research Triangle97.497.894.097.497.885.0
New York City88.4(1)85.392.388.485.392.3
Texas95.595.191.291.891.581.6
Subtotal94.894.995.190.090.789.9
Canada95.987.180.882.973.068.2
Non-cluster/other markets72.578.575.072.578.575.0
North America94.6%(2)94.6%94.8%89.7%90.2%89.4%

(1)The Alexandria Center® for Life Science – New York City Megacampus is 98.7% occupied as of December 31, 2024. Occupancy percentage in our New York City market

reflects vacancy at the Alexandria Center® for Life Science – Long Island City property, which was 45.7% occupied as of December 31, 2024.

(2)Includes temporary vacancy as of December 31, 2024 aggregating 278,528 RSF that is leased and expected to be occupied upon completion of the tenant improvement

to the spaces. The weighted-average expected delivery date of these spaces is May 12, 2025.

Top 20 tenants

92% of Top 20 Tenant Annual Rental Revenue Is From Investment-Grade

or Publicly Traded Large Cap Tenants**(1)**

Our properties are leased to a high-quality and diverse group of tenants, with no individual tenant accounting for more than 4.3%

of our annual rental revenue in effect as of December 31, 2024. The following table sets forth information regarding leases with our 20

largest tenants in North America based upon annual rental revenue in effect as of December 31, 2024 (dollars in thousands, except

average market cap amounts):

Remaining Lease Term(1) (in Years)Aggregate RSFAnnual Rental Revenue(1)Percentage of Annual Rental Revenue(1)Investment-Grade Credit RatingsAverage Market Cap (in billions)
TenantMoody’sS&P
1Eli Lilly and Company8.41,122,777$90,2594.3%A1A+$769.8
2Moderna, Inc.11.3634,04590,1034.3——$35.1
3Bristol-Myers Squibb Company5.4999,37977,1883.7A2A$100.6
4Takeda Pharmaceutical Company Limited10.4549,75947,8992.3Baa1BBB+$44.2
5Roche8.2647,06937,4051.8Aa2AA$232.8
6Illumina, Inc.5.9857,96735,9241.7Baa3BBB$20.6
7Alphabet Inc.2.8625,01534,8991.7Aa2AA+$2,032.2
82seventy bio, Inc.(2)8.7312,80533,5431.6——$0.2
9United States Government5.6429,35928,8611.4AaaAA+$—
10Cloud Software Group, Inc.2.2(3)292,01328,5371.4——$—
11Novartis AG3.5448,69027,9581.3Aa3AA-$235.1
12Uber Technologies, Inc.57.8(4)1,009,18827,7871.3Baa2BBB-$147.7
13AstraZeneca PLC4.8450,84827,2261.3A2A+$226.6
14Boston Children's Hospital12.2309,23126,1541.2Aa2AA$—
15The Regents of the University of California6.4372,64723,5151.1Aa2AA$—
16Sanofi6.0267,27821,4441.0A1AA$127.9
17Merck & Co., Inc.8.5337,70321,4011.0A1A+$300.0
18New York University7.1218,98321,0561.0Aa2AA-$—
19Charles River Laboratories, Inc.10.3255,63520,5781.0——$11.1
20Massachusetts Institute of Technology5.0237,84920,2281.0AaaAAA$—
Total/weighted-average9.3(4)10,378,240$741,96535.4%

Annual rental revenue and RSF include 100% of each property managed by us in North America. Refer to “Annual rental revenue” and “Investment-grade or publicly traded large

cap tenants” under “Definitions and reconciliations” in Item 7 for additional details, including our methodologies of calculating annual rental revenue from unconsolidated real

estate joint ventures and average market capitalization, respectively.

(1)Based on total annual rental revenue in effect as of December 31, 2024.

(2)Includes approximately 195,000 RSF, or 62.8% of the annual rental revenue generated from 2seventy bio as of December 31, 2024, that is subleased to Regeneron

Pharmaceuticals, Inc., an investment-grade publicly traded biotechnology company. As of September 30, 2024, 2seventy bio, Inc. held $192.4 million of cash, cash

equivalents, and marketable securities. Additionally, 90.2% of the annual rental revenue generated by 2seventy bio is guaranteed by another related public biotechnology

company.

(3)Consists of one lease at a property acquired in 2022 with future development and redevelopment opportunities. This lease with Cloud Software Group, Inc. (formerly known

as TIBCO Software, Inc.) was in place when we acquired the property.

(4)Includes (i) ground leases for land at 1455 and 1515 Third Street (two buildings aggregating 422,980 RSF) and (ii) leases at 1655 and 1725 Third Street (two buildings

aggregating 586,208 RSF) in our Mission Bay submarket owned by our unconsolidated real estate joint venture in which we have an ownership interest of 10%. Annual

rental revenue is presented using 100% of the annual rental revenue from our consolidated properties and our share of annual rental revenue from our unconsolidated real

estate joint ventures. Excluding these ground leases, the weighted-average remaining lease term for our top 20 tenants was 7.5 years as of December 31, 2024.

Stable Cash Flows From Our High-Quality and Diverse Mix of Approximately 800 Tenants
Investment-Grade or Publicly Traded Large Cap Tenants
92%
of ARE’s Top 20 Tenant Annual Rental Revenue
52%
Percentage of ARE’s Annual Rental Revenueof ARE’s Annual Rental Revenue
Solid Historical Occupancy of 96% Over Past 10 Years**(2)** From Historically Strong Demand for Our Class A/A+ Properties in AAA Locations
Annual Rental RevenueOccupancy Across Key Locations
Percentage of ARE’s Annual Rental Revenue

Multinational

Pharmaceutical

Life Science

Product,

Service, and

Device

Public

Biotechnology -

Approved or

Marketed

Product

Public

Biotechnology -

Preclinical or

Clinical Stage

Private

Biotechnology

Other(1)

Other Investment-Grade

or Large Cap Tech

Biomedical and

Government

Institutions

11544872092069

Megacampus**™**

Core and

Non-Core

9345848836606

(3)

7696581395165

As of December 31, 2024. Annual rental revenue represents amounts in effect as of December 31, 2024. Refer to “Definitions and reconciliations” in Item 7 for additional

information.

(1)Represents the percentage of our annual rental revenue generated by technology, professional services, finance, telecommunications, and construction/real estate

companies, as well as retail-related tenants, which generate less than 1.0% of our annual rental revenue.

(2)Represents the average occupancy percentage of operating properties as of each December 31 from 2015 through 2024.

(3)Refer to footnote 1 under “Summary of occupancy percentages in North America” in Item 2 for additional details.

Long-Duration and Stable Cash Flows From High-Quality and Diverse Tenants
Long-Duration Lease Terms
9.3 Years
Top 20 Tenants
7.5 Years
All Tenants
Weighted-Average Remaining Term(1)
Sustained Strength in Tenant Collections(2)
99.9%
For the Three Months Ended December 31, 2024
99.5%
January 2025

(1)Based on annual rental revenue in effect as of December 31, 2024.

(2)Represents the portion of total receivables billed for each indicated period collected as of the date of this report.

Property listing

Our Megacampus**™** Properties Account for 77% of Our Annual Rental Revenue

The following table provides certain information about our properties as of December 31, 2024 (dollars in thousands):

Occupancy Percentage
RSFNumber of PropertiesAnnual Rental Revenue
OperatingOperating and Redevelopment
Market / Submarket / AddressOperatingDevelopmentRedevelopmentTotal
Greater Boston
Cambridge/Inner Suburbs
Megacampus: Alexandria Center**®** at Kendall Square2,199,030——2,199,0307$228,062100.0%100.0%
50*(1), 60(1), 75/125(1), 100(1), and 225(1)* Binney Street, 140 First Street, and 300 Third Street*(1)*
Megacampus: Alexandria Center**®** at One Kendall Square1,281,580—104,9561,386,53612145,57694.887.6
One Kendall Square (Buildings 100, 200, 300, 400, 500, 600/700, 1400, 1800, and 2000), 325 and 399 Binney Street, and One Hampshire Street
Megacampus: Alexandria Technology Square**®**1,185,190——1,185,1907110,96997.797.7
100, 200, 300, 400, 500, 600, and 700 Technology Square
Megacampus: The Arsenal on the Charles776,78136,444308,4461,121,6711347,73099.471.2
311, 321, and 343 Arsenal Street, 300, 400, and 500 North Beacon Street, 1, 2, 3, and 4 Kingsbury Avenue, and 100, 200, and 400 Talcott Avenue
Megacampus: 480 Arsenal Way, 446, 458, 500, 550 Arsenal Street, and 99 Coolidge Avenue**(1)**633,056204,395—837,451628,17398.498.4
Cambridge/Inner Suburbs6,075,637240,839413,4026,729,87845560,51098.291.9
Fenway
Megacampus: Alexandria Center**®** for Life Science – Fenway1,291,019392,011137,6751,820,7053.0100,58789.781.1
401 and 421*(1)* Park Drive and 201 Brookline Avenue*(1)*
Seaport Innovation District
5 and 15(1) Necco Street441,396——441,396244,14381.881.8
Seaport Innovation District441,396——441,396244,14381.881.8
Route 128
Megacampus: Alexandria Center**®** for Life Science – Waltham466,094—596,0641,062,158536,659100.043.9
40, 50, and 60 Sylvan Road, 35 Gatehouse Drive, and 840 Winter Street
19, 225, and 235 Presidential Way585,226——585,226313,937100.0100.0
Route 1281,051,320—596,0641,647,384850,596100.063.8
Other400,863—453,869854,73264,72859.728.0
Greater Boston9,260,235632,8501,601,01011,494,09564$760,56494.8%80.8%
Refer to “New Class A/A+ development and redevelopment properties: summary of pipeline” in Item 2 and “Megacampus” under “Definitions and reconciliations” in Item 7 for additional details. (1)We own a partial interest in this property through a real estate joint venture. Refer to “Consolidated and unconsolidated real estate joint ventures” in Item 7 for additional details.

Property listing (continued)

Occupancy Percentage
RSFNumber of PropertiesAnnual Rental Revenue
OperatingOperating and Redevelopment
Market / Submarket / AddressOperatingDevelopmentRedevelopmentTotal
San Francisco Bay Area
Mission Bay
Megacampus: Alexandria Center**®** for Science and Technology – Mission Bay**(1)**2,005,369109,435—2,114,80410$90,45295.1%95.1%
1455*(2), 1515(2), 1655, and 1725 Third Street, 409 and 499 Illinois Street,* 1450*(3), 1500, and 1700 Owens Street, and 455 Mission Bay Boulevard* South
Mission Bay2,005,369109,435—2,114,8041090,45295.195.1
South San Francisco
Megacampus: Alexandria Technology Center**®** – Gateway**(1)**1,408,022—259,6891,667,7111276,70581.969.1
600*(2), 601, 611, 630(2), 650(2), 651, 681, 685, 701, 751, 901(2), and 951(2)* Gateway Boulevard
Megacampus: Alexandria Center**®** for Advanced Technologies – South San Francisco812,453—107,250919,703552,990100.088.3
213*(1)**, 249, 259, 269, and 279 East Grand Avenue*
Alexandria Center® for Life Science – South San Francisco504,053——504,053332,76793.993.9
201 Haskins Way and 400 and 450 East Jamie Court
Megacampus: Alexandria Center**®** for Advanced Technologies – Tanforan445,232——445,23223,829100.0100.0
1122 and 1150 El Camino Real
Alexandria Center® for Life Science – Millbrae(1)—285,346—285,3461—N/AN/A
230 Harriet Tubman Way
500 Forbes Boulevard(1)155,685——155,685110,680100.0100.0
South San Francisco3,325,445285,346366,9393,977,73024176,97191.482.3
Greater Stanford
Megacampus: Alexandria Center**®** for Life Science – San Carlos738,038——738,038941,67194.594.5
825, 835, 960, and 1501-1599 Industrial Road
Alexandria Stanford Life Science District704,560——704,560975,77198.598.5
3160, 3165, 3170, and 3181 Porter Drive and 3301, 3303, 3305, 3307, and 3330 Hillview Avenue
3412, 3420, 3440, 3450, and 3460 Hillview Avenue340,103——340,103523,60382.982.9
3875 Fabian Way228,000——228,00019,402100.0100.0
2475 and 2625/2627/2631 Hanover Street and 1450 Page Mill Road198,558——198,558315,90289.489.4
2100, 2200, and 2400 Geng Road78,501——78,50134,803100.0100.0
3350 West Bayshore Road61,431——61,43114,770100.0100.0
Greater Stanford2,349,191——2,349,19131175,92294.594.5
San Francisco Bay Area7,680,005394,781366,9398,441,72565$443,34593.3%89.1%
Refer to “New Class A/A+ development and redevelopment properties: summary of pipeline” in Item 2 and “Megacampus” under “Definitions and reconciliations” in Item 7 for additional details. (1)We own a partial interest in this property through a real estate joint venture. Refer to “Consolidated and unconsolidated real estate joint ventures” in Item 7 for additional details. (2)We own 100% of this property. (3)During the three months ended December 31, 2024, we executed a letter of intent with a biomedical institution for the sale of a condominium interest aggregating 103,361 RSF, or approximately 49% of the development project, with the transaction expected to close in 2025. Accordingly, we adjusted the development project RSF and its related book value to reflect 109,435 RSF, with our ownership share expected to be 25% at completion of the project. Refer to “New Class A/A+ development and redevelopment properties: current projects” in Item 2 for additional details.

Property listing (continued)

Occupancy Percentage
RSFNumber of PropertiesAnnual Rental Revenue
OperatingOperating and Redevelopment
Market / Submarket / AddressOperatingDevelopmentRedevelopmentTotal
San Diego
Torrey Pines
Megacampus: One Alexandria Square840,192241,504—1,081,69610$47,91599.0%99.0%
3115 and 3215*(1)* Merryfield Row, 3010, 3013, and 3033 Science Park Road, 10935, 10945, 10955, and 10970 Alexandria Way, 10996 Torreyana Road, and 3545 Cray Court
ARE Torrey Ridge299,138——299,138313,26379.779.7
10578, 10618, and 10628 Science Center Drive
ARE Nautilus218,459——218,459412,18497.797.7
3530 and 3550 John Hopkins Court and 3535 and 3565 General Atomics Court
Torrey Pines1,357,789241,504—1,599,2931773,36294.594.5
University Town Center
Megacampus: Campus Point by Alexandria**(1)**1,594,463426,927—2,021,3901086,46998.098.0
9880*(2)**, 10210, 10260, 10290, and 10300 Campus Point Drive and 4135, 4155,* 4161, 4224, and 4242 Campus Point Court
Megacampus: 5200 Illumina Way**(1)**792,687——792,687629,978100.0100.0
9625 Towne Centre Drive(1)163,648——163,64816,520100.0100.0
University Town Center2,550,798426,927—2,977,72517122,96798.898.8
Sorrento Mesa
Megacampus: SD Tech by Alexandria**(1)**878,805253,079—1,131,8841239,98893.693.6
9605, 9645, 9675, 9725, 9735, 9808, 9855, and 9868 Scranton Road, 5505 Morehouse Drive*(2)**, and 10055, 10065, and 10075 Barnes Canyon Road*
Megacampus: Sequence District by Alexandria801,575——801,575728,766100.0100.0
6260, 6290, 6310, 6340, 6350, 6420, and 6450 Sequence Drive
Pacific Technology Park(1)544,352——544,35259,35292.892.8
9389, 9393, 9401, 9455, and 9477 Waples Street
Summers Ridge Science Park(1)316,531——316,531411,521100.0100.0
9965, 9975, 9985, and 9995 Summers Ridge Road
Scripps Science Park by Alexandria144,113——144,113111,379100.0100.0
10102 Hoyt Park Drive
ARE Portola101,857——101,85734,022100.0100.0
6175, 6225, and 6275 Nancy Ridge Drive
5810/5820 Nancy Ridge Drive83,354——83,35414,581100.0100.0
9877 Waples Street63,774——63,77412,680100.0100.0
5871 Oberlin Drive33,842——33,84211,909100.0100.0
Sorrento Mesa2,968,203253,079—3,221,28235$114,19896.8%96.8%
Refer to “New Class A/A+ development and redevelopment properties: summary of pipeline” in Item 2 and “Megacampus” under “Definitions and reconciliations” in Item 7 for additional details. (1)We own a partial interest in this property through a real estate joint venture. Refer to “Consolidated and unconsolidated real estate joint ventures” in Item 7 for additional details. (2)We own 100% of this property.

Property listing (continued)

Occupancy Percentage
RSFNumber of PropertiesAnnual Rental Revenue
OperatingOperating and Redevelopment
Market / Submarket / AddressOperatingDevelopmentRedevelopmentTotal
San Diego (continued)
Sorrento Valley
3911, 3931, and 3985 Sorrento Valley Boulevard151,406——151,4066$3,97054.0%54.0%
11045 and 11055 Roselle Street43,233——43,23322,203100.0100.0
Sorrento Valley194,639——194,63986,17364.264.2
Other311,021——311,021210,225100.0100.0
San Diego7,382,450921,510—8,303,96079326,92596.396.3
Seattle
Lake Union
Megacampus: Alexandria Center**®** for Life Science – Eastlake1,152,644——1,152,644977,46195.695.6
1150, 1201*(1),* 1208*(1),* 1551, 1600, and 1616 Eastlake Avenue East, 188 and 199*(1)* East Blaine Street, and 1600 Fairview Avenue East
Megacampus: Alexandria Center**®** for Life Science – South Lake Union381,380227,577—608,957321,89099.699.6
400*(1)* and 701 Dexter Avenue North and 428 Westlake Avenue North
219 Terry Avenue North31,797——31,79711,33956.956.9
Lake Union1,565,821227,577—1,793,39813100,69095.895.8
Elliott Bay
410 West Harrison Street and 410 Elliott Avenue West20,101——20,1012710100.0100.0
Bothell
Megacampus: Alexandria Center**®** for Advanced Technologies – Canyon Park1,061,778——1,061,7782221,48287.787.7
22121 and 22125 17th Avenue Southeast, 22021, 22025, 22026, 22030, 22118, and 22122 20th Avenue Southeast, 22333, 22422, 22515, 22522, 22722, and 22745 29th Drive Southeast, 21540, 22213, and 22309 30th Drive Southeast, and 1629, 1631, 1725, 1916, and 1930 220th Street Southeast
Alexandria Center® for Advanced Technologies – Monte Villa Parkway463,449——463,449612,29090.390.3
3301, 3303, 3305, 3307, 3555, and 3755 Monte Villa Parkway
Bothell1,525,227——1,525,2272833,77288.588.5
Other75,663——75,663284298.598.5
Seattle3,186,812227,577—3,414,38945$136,01492.4%92.4%
Refer to “New Class A/A+ development and redevelopment properties: summary of pipeline” in Item 2 and “Megacampus” under “Definitions and reconciliations” in Item 7 for additional details. (1)We own a partial interest in this property through a real estate joint venture. Refer to “Consolidated and unconsolidated real estate joint ventures” in Item 7 for additional details.

Property listing (continued)

Occupancy Percentage
RSFNumber of PropertiesAnnual Rental Revenue
OperatingOperating and Redevelopment
Market / Submarket / AddressOperatingDevelopmentRedevelopmentTotal
Maryland
Rockville
Megacampus: Alexandria Center**®** for Life Science – Shady Grove1,692,350——1,692,35020$79,07697.5%97.5%
9601, 9603, 9605, 9704, 9708, 9712, 9714, 9800, 9804, 9808, 9900, and 9950 Medical Center Drive, 14920 and 15010 Broschart Road, 9920 Belward Campus Drive, and 9810 and 9820 Darnestown Road
1330 Piccard Drive131,508——131,50814,323100.0100.0
1405 and 1450(1) Research Boulevard114,849——114,84923,02973.373.3
1500 and 1550 East Gude Drive91,359——91,35921,844100.0100.0
5 Research Place63,852——63,85213,082100.0100.0
5 Research Court51,520——51,52011,976100.0100.0
12301 Parklawn Drive49,185——49,18511,598100.0100.0
Rockville2,194,623——2,194,6232894,92896.796.7
Gaithersburg
Alexandria Technology Center® – Gaithersburg I619,061——619,061919,60393.693.6
9, 25, 35, 45, 50, and 55 West Watkins Mill Road and 910, 930, and 940 Clopper Road
Alexandria Technology Center® – Gaithersburg II486,301——486,301718,816100.0100.0
700, 704, and 708 Quince Orchard Road and 19, 20, 21, and 22 Firstfield Road
20400 Century Boulevard81,006——81,00612,107100.0100.0
401 Professional Drive63,154——63,15411,94990.190.1
950 Wind River Lane50,000——50,00011,234100.0100.0
620 Professional Drive27,950——27,95011,207100.0100.0
Gaithersburg1,327,472——1,327,4722044,91696.696.6
Beltsville
8000/9000/10000 Virginia Manor Road191,884——191,88412,97497.797.7
101 West Dickman Street(1)135,949——135,94911,21469.969.9
Beltsville327,833——327,83324,18886.186.1
Maryland3,849,928——3,849,92850144,03295.795.7
Research Triangle
Research Triangle
Megacampus: Alexandria Center**®** for Life Science – Durham2,214,887——2,214,88716$55,24297.697.6
6, 8, 10, 12, 14, 40, 41, 42, and 65 Moore Drive, 21, 25, 27, 29, and 31 Alexandria Way, 2400 Ellis Road, and 14 TW Alexander Drive
Megacampus: Alexandria Center**®** for Advanced Technologies and AgTech – Research Triangle687,824——687,824631,93999.499.4
6, 8, 10, and 12 Davis Drive and 5 and 9 Laboratory Drive
Megacampus: Alexandria Center**®** for Sustainable Technologies364,493——364,4937$11,97991.8%91.8%
104, 108, 110, 112, and 114 TW Alexander Drive and 5 and 7 Triangle Drive
Refer to “New Class A/A+ development and redevelopment properties: summary of pipeline” in Item 2 and “Megacampus” under “Definitions and reconciliations” in Item 7 for additional details. (1)We own a partial interest in this property through a real estate joint venture. Refer to “Consolidated and unconsolidated real estate joint ventures” in Item 7 for additional details.

Property listing (continued)

Occupancy Percentage
RSFNumber of PropertiesAnnual Rental Revenue
OperatingOperating and Redevelopment
Market / Submarket / AddressOperatingDevelopmentRedevelopmentTotal
Research Triangle (continued)
Research Triangle (continued)
Alexandria Technology Center® – Alston155,731——155,7313$4,12694.7%94.7%
100, 800, and 801 Capitola Drive
Alexandria Innovation Center® – Research Triangle136,722——136,72234,23599.299.2
7010, 7020, and 7030 Kit Creek Road
2525 East NC Highway 5482,996——82,99613,651100.0100.0
407 Davis Drive81,956——81,95613,323100.0100.0
601 Keystone Park Drive77,595——77,59512,313100.0100.0
Research Triangle3,802,204——3,802,20438116,80897.497.4
New York City
New York City
Megacampus: Alexandria Center**®** for Life Science – New York City742,586——742,586367,86498.798.7
430 and 450 East 29th Street
Alexandria Center® for Life Science – Long Island City179,188——179,18815,67045.745.7
30-02 48th Avenue
New York City921,774——921,774473,53488.488.4
Texas
Austin
Megacampus: Intersection Campus1,525,359——1,525,3591239,95599.299.2
507 East Howard Lane, 13011 McCallen Pass, 13813 and 13929 Center Lake Drive, and 12535, 12545, 12555, and 12565 Riata Vista Circle
1001 Trinity Street and 1020 Red River Street198,972——198,9722895100.0100.0
Austin1,724,331——1,724,3311440,85099.399.3
Greater Houston
Alexandria Center® for Advanced Technologies at The Woodlands120,828—73,298194,12613,17241.525.8
8800 Technology Forest Place
Texas1,845,159—73,2981,918,4571544,02295.591.8
Canada888,189—139,3111,027,5001119,66195.982.9
Non-cluster/other markets349,099——349,0991015,02772.572.5
North America, excluding properties held for sale39,165,8552,176,7182,180,55843,523,1313812,079,93294.6%89.7%
Properties held for sale600,870——600,8701013,05639.6%39.6%
Total – North America39,766,7252,176,7182,180,55844,124,001391$2,092,988

Refer to “New Class A/A+ development and redevelopment properties: summary of pipeline” in Item 2 and “Megacampus” under “Definitions and reconciliations” in Item 7 for additional details.

Leasing activity

During the year ended December 31, 2024, strong demand for our high-quality Class A/A+ properties translated into solid

leasing activity and rental rate growth in 2024 for our overall portfolio and our development and redevelopment pipeline.

  • Executed a total of 209 leases, with a weighted-average lease term of 8.9 years, for 5.1 million RSF;

  • 84% of our leasing activity during the last twelve months was generated from our existing tenant base;

  • Annual leasing activity of 3.9 million RSF for renewed and re-leased spaces; and

  • Annual rental rate increases of 16.9% and 7.2% (cash basis) on renewed and re-leased space.

During the year ended December 31, 2024, we granted tenant concessions/free rent averaging 0.7 months per annum with

respect to the 5.1 million RSF leased.

Lease structure

Our Same Properties total revenue growth was 2.7% during the year ended December 31, 2024, and our Same Properties net

operating income and Same Properties net operating income increases (cash basis) for the year ended December 31, 2024 were 1.2%

and 4.6%, respectively. Rental rate increases for the year ended December 31, 2024 of 16.9% and 7.2% (cash basis) on 3.9 million

renewed/re-leased RSF are attributable to the sustained appeal of our properties, strong property management expertise of our team,

and effective operational strategies. Additionally, a favorable triple net lease structure with contractual annual rent escalations resulted

in both a consistent Same Properties operating margin of 68% and Same Properties current-period average occupancy of 94.2% for the

year ended December 31, 2024, an increase of 30 bps for the same-period prior-year average, across our 321 Same Properties

aggregating 31.7 million RSF. As of December 31, 2024, approximately 92% of our leases (on an annual rental revenue basis) were

triple net leases, which require tenants to pay substantially all real estate taxes, insurance, utilities, repairs and maintenance, common

area expenses, and other operating expenses (including increases thereto) in addition to base rent. Additionally, approximately 97% of

our leases (on an annual rental revenue basis) contained contractual annual rent escalations approximating 3% that were either fixed or

based on a consumer price index or another index, and approximately 92% of our leases (on an annual rental revenue basis) provided

for the recapture of certain capital expenditures.

Leasing activity (continued)

The following table summarizes our leasing activity at our properties for the years ended December 31, 2024 and 2023:

Year Ended December 31,
20242023
Including Straight-Line RentCash BasisIncluding Straight-Line RentCash Basis
(Dollars per RSF)
Leasing activity:
Renewed/re-leased space(1)
Rental rate changes16.9%7.2%29.4%15.8%
New rates$65.48$64.18$52.35$50.82
Expiring rates$56.01$59.85$40.46$43.87
RSF3,888,1393,046,386
Tenant improvements/leasing commissions$46.89(2)$26.09
Weighted-average lease term8.5 years8.7 years
Developed/redeveloped/previously vacant space leased(3)
New rates$59.44$57.34$65.66$59.74
RSF1,165,8151,259,686
Weighted-average lease term10.0 years13.8 years
Leasing activity summary (totals):
New rates$64.16$62.68$56.09$53.33
RSF5,053,9544,306,072
Weighted-average lease term8.9 years11.3 years
Lease expirations*(1)*
Expiring rates$53.82$57.24$43.84$45.20
RSF5,005,6385,027,773

Leasing activity includes 100% of results for properties in North America in which we have an investment.

(1)Excludes month-to-month leases aggregating 136,131 RSF and 86,092 RSF as of December 31, 2024 and 2023, respectively. During the year ended

December 31, 2024, we granted free rent concessions averaging 0.7 months per annum.

(2)Includes tenant improvements and leasing commissions for leases aggregating 319,708 RSF related to (i) a 10-year lease with an anchor tenant expanding into its

flagship building in our Greater Stanford submarket and (ii) a 10-year lease, with rental rate increases of 83.3% and 42.3% (cash basis), in our Torrey Pines

submarket with an investment-grade top 20 tenant. Excluding these leases, tenant improvements and leasing commissions per RSF for the year ended

December 31, 2024 was $32.83, which is consistent with the five-year quarterly average of $29.98 per RSF. Tenant improvements and leasing commissions on

renewed and re-leased space executed during the year ended December 31, 2024 represented only 8.4% of total lease term rents, the second lowest percentage

of total lease term rents in the past five years.

(3)Refer to “New Class A/A+ development and redevelopment properties: summary of pipeline” in Item 2 for additional information, including total project costs.

Summary of contractual lease expirations

The following table summarizes the contractual lease expirations at our properties as of December 31, 2024:

YearRSFPercentage of Occupied RSFAnnual Rental Revenue (per RSF)(1)Percentage of Annual Rental Revenue
2025(2)3,708,19510.0%$45.918.2%
20262,826,9937.7%$50.736.9%
20273,302,5988.9%$53.808.6%
20283,944,44010.7%$49.789.5%
20292,385,9146.5%$51.305.9%
20303,144,5618.5%$43.116.5%
20313,433,9589.3%$54.769.1%
20321,005,6892.7%$58.962.9%
20332,585,8137.0%$47.775.9%
20343,304,1058.9%$66.9010.6%
Thereafter7,291,85519.8%$73.8525.9%

Contractual lease expirations for properties classified as held for sale as of December 31, 2024 are excluded from the information on this page.

(1)Represents amounts in effect as of December 31, 2024.

(2)Excludes month-to-month leases aggregating 136,131 RSF as of December 31, 2024.

Summary of contractual lease expirations (continued)

The following tables present our lease expirations by market for 2025 and 2026 as of December 31, 2024:

2025 Contractual Lease Expirations (in RSF)Annual Rental Revenue (per RSF)(4)
MarketLeasedNegotiating/ AnticipatingTargeted for Future Development/ Redevelopment(1)Remaining Expiring Leases(2)Total(3)
Greater Boston127,80499,20125,312364,741617,058$42.40
San Francisco Bay Area245,347184,286—308,637738,27073.49
San Diego144,67318,813278,606202,285644,37720.58
Seattle—12,237—177,932190,16925.16
Maryland51,593——141,349192,94226.28
Research Triangle11,63216,334—170,938198,90444.71
New York City—27,912—40,34768,259110.42
Texas——198,972—198,972N/A
Canada22,991——65,87388,86420.03
Non-cluster/other markets———2,3002,30040.17
Subtotal604,040358,783502,8901,474,4022,940,11541.78
Key 1Q25 lease expirations(5)23,522112,831—631,727768,08061.67
Total627,562471,614502,8902,106,1293,708,195$45.91
Percentage of expiring leases17%13%14%56%100%
2026 Contractual Lease Expirations (in RSF)Annual Rental Revenue (per RSF)(4)
MarketLeasedNegotiating/ AnticipatingTargeted for Future Development/ RedevelopmentRemaining Expiring Leases(2)Total
Greater Boston46,8589,874—391,196447,928$54.42
San Francisco Bay Area1,6194,753—511,665518,03766.72
San Diego———822,140822,14049.60
Seattle—18,205—102,551120,75643.62
Maryland———321,676321,67623.61
Research Triangle—19,753—115,221134,97445.64
New York City—104,157—71,470175,62793.58
Texas——————
Canada—247,743——247,74322.24
Non-cluster/other markets———38,11238,11270.34
Total48,477404,485—2,374,0312,826,993$50.73
Percentage of expiring leases2%14%0%84%100%

Contractual lease expirations for properties classified as held for sale as of December 31, 2024 are excluded from the information on this page.

(1)Primarily represents assets that were recently acquired for future development and redevelopment opportunities, for which we expect, subject to market conditions and

leasing, to commence first-time conversion from non-laboratory space to laboratory space, or to commence future ground-up development. As of December 31, 2024, the

weighted-average annual rental revenue and expiration date of these leases expiring in 2025 is $7.0 million and February 18, 2025, respectively. Refer to “Investments in

real estate” under “Definitions and reconciliations” in Item 7 for additional details, including development and redevelopment square feet currently included in rental

properties.

(2)The largest remaining contractual lease expiration in 2025 is 98,741 RSF in our Sorrento Mesa submarket, where we are in early discussions to renew the tenant for a

short-term extension, and in 2026 is 163,648 RSF in our University Town Center submarket, where we have an ownership interest of 30.0% and are evaluating options to

re-lease or reposition the space from single tenancy to multi-tenancy.

(3)Excludes month-to-month leases aggregating 136,131 RSF as of December 31, 2024. Refer to “Leasing activity” in Item 2 for additional details.

(4)Represents amounts in effect as of December 31, 2024.

(5)Includes expected temporary vacancies aggregating 768,080 RSF in four submarkets with a weighted-average expiration date of January 21, 2025 and annual rental

revenue aggregating approximately $47 million with our share of this annual rental revenue aggregating $35 million comprising the following: (i) 182,054 RSF at Alexandria

Technology Square® Megacampus in our Cambridge submarket, (ii) 234,249 RSF at 409 Illinois Street, where we have an ownership interest of 25.0%, in our Mission Bay

submarket, (iii) one property aggregating 104,531 RSF in our Research Triangle market, and (iv) two properties aggregating 247,246 RSF in our Austin submarket. We

expect downtime on the 768,080 RSF to range from 12 to 24 months on a weighted-average basis. Our guidance assumes these properties remain operating properties

and are included in our same property pool for the year ending December 31, 2025. As of December 31, 2024, 23,522 RSF was leased, 112,831 RSF was under signed

letters of intent to re-lease, 527,196 RSF was involved in ongoing discussions for re-lease, and we expect to favorably resolve the remaining 104,531 RSF over the next

several quarters.

Investments in real estate

A key component of our business model is our disciplined allocation of capital to the development and redevelopment of new

Class A/A+ properties, and property enhancements identified during the underwriting of certain acquired properties, primarily located in

collaborative Megacampus ecosystems in AAA life science innovation clusters. These projects are focused on providing high-quality,

generic, and reusable spaces that meet the real estate requirements of a wide range of tenants. Upon completion, each development or

redevelopment project is expected to generate increases in rental income, net operating income, and cash flows. Our development and

redevelopment projects are generally in locations that are highly desirable to high-quality entities, which we believe results in higher

occupancy levels, longer lease terms, higher rental income, higher returns, and greater long-term asset value. Our pre-construction

activities are undertaken in order to prepare the property for its intended use and include entitlements, permitting, design, site work, and

other activities preceding commencement of construction of aboveground building improvements.

Our investments in real estate consisted of the following as of December 31, 2024 (dollars in thousands):

Development and Redevelopment
Future Opportunities Subject to Market Conditions and Leasing
OperatingUnder ConstructionPriority AnticipatedFutureSubtotalTotal
Square footage
Operating39,165,855————39,165,855
New Class A/A+ development and redevelopment properties—4,357,2762,134,94823,696,28030,188,50430,188,504
Future development and redevelopment square feet currently included in rental properties(1)——(213,524)(2,843,150)(3,056,674)(3,056,674)
Total square footage, excluding properties held for sale39,165,8554,357,2761,921,42420,853,13027,131,83066,297,685
Properties held for sale600,870——2,390,8562,390,8562,991,726
Total square footage39,766,7254,357,2761,921,42423,243,98629,522,68669,289,411(2)
Investments in real estate
Gross book value as of December 31, 2024(3)$28,878,752$3,893,557$510,372$4,452,537$8,856,466$37,735,218

(1)Refer to “Investments in real estate” under “Definitions and reconciliations” in Item 7 for additional details, including future development and redevelopment square feet

currently included in rental properties.

(2)We expect to continue pursuing our strategy to fund a significant portion of our capital requirements for the year ending December 31, 2025 with dispositions and sales

of partial interests primarily focused on sales of properties and land parcels not integral to our Megacampus strategy.

(3)Balances exclude accumulated depreciation and our share of the cost basis associated with our properties held by our unconsolidated real estate joint ventures, which is

classified as investments in unconsolidated real estate joint ventures in our consolidated balance sheet.

Acquisitions

Our real estate asset acquisitions during the year ended December 31, 2024, consisted of the following (dollars in thousands):

PropertySubmarket/MarketDate of PurchaseNumber of PropertiesOperating OccupancySquare FootagePurchase Price
Future Development(1)Operating With Future Development/ Redevelopment(1)
Completed during the year ended December 31, 2024:
285, 299, 307, and 345 Dorchester Avenue (60% interest in consolidated JV)(2)Seaport Innovation District/ Greater Boston1/30/24—N/A1,040,000—$155,321
428 Westlake Avenue NorthLake Union/Seattle10/1/241100%—90,62647,600
Other46,490
Total 2024 acquisitions$249,411

(1)We expect to provide total estimated costs and related yields for development and significant redevelopment projects in the future, subsequent to the commencement of construction.

(2)Refer to Note 4 – “Consolidated and unconsolidated real estate joint ventures” to our consolidated financial statements in Item 15 for additional details.

Dispositions

Our completed dispositions of real estate assets during the year ended December 31, 2024, consisted of the following (dollars in thousands, except for sales price per RSF):

PropertySubmarket/MarketDate of SaleInterest SoldRSFCapitalization RateCapitalization Rate (Cash Basis)Sales PriceSeller Financing(1)Sales Price per RSFGain on Sale of Real Estate(2)
Stabilized Properties
One Moderna WayRoute 128/Greater Boston12/17/24100%722,1308.5%6.3%$369,439$512$—
1165 Eastlake Avenue EastLake Union/Seattle9/12/24100%100,0864.7%4.9%149,985$1,49921,535
14225 Newbrook DriveNorthern Virginia/Maryland10/15/24100%248,1867.6%7.4%80,500$32437,074
6040 George Watts Hill DriveResearch Triangle/Research Triangle12/10/24100%149,5858.0%7.1%93,500$6255,004
Other90,1219,621
783,545
Properties with vacancy or significant near-term capital requirements
215 First StreetCambridge/Greater Boston12/20/24100%369,520(3)(3)245,539(3)(3)—
150 Second Street, and 11 Hurley StreetCambridge/Greater Boston182,993
4755 and 4757 Nexus Center Drive and 4796 Executive Drive(4)University Town Center/San Diego12/30/24100%177,804(4)(4)120,000(4)$79,166$67547,511
219 East 42nd StreetNew York City/New York City7/9/24100%349,947N/AN/A60,000$171—
Other51,106392
476,645
Land and other
99 A StreetSeaport Innovation District/ Greater Boston3/8/24100%235,000(5)(5)13,350—
10048 and 10219 Meanley Drive and 10277 Scripps Ranch BoulevardSorrento Mesa/San Diego12/20/24100%444,041(5)(5)55,00025,000—
9444 Waples Street (50% consolidated JV)Sorrento Mesa/San Diego12/23/24(6)149,000(6)(6)31,000(6)8,175(6)
Other(7)(7)22,913(7)(7)
122,263
Total 2024 dispositions$1,382,453$104,166$129,312
Our share of 2024 dispositions, including amounts recognized in equity in earnings$1,366,953$127,615(8)

(1)Refer to “Notes receivable” in Note 8 – “Other assets” to our consolidated financial statements in Item 15 for additional information.

(2)Refer to “Sales of real estate assets and impairment charges” in Note 3 – “Investments in real estate” to our consolidated financial statements in Item 15 for additional information.

(3)Represents properties that were 87% occupied as of September 30, 2024, with 61% of the aggregate RSF, primarily located at 215 First Street, scheduled to expire by December 31, 2025. These properties were not core to our

Megacampus strategy due to their size, location, or existing use. They are also expected to require significant re-leasing capital over the next few years, including at 215 First Street, a historical building with infrastructure limitations with

challenging floor plates. Acquired in 2007, 215 First Street came with significant entitlements which were later used to develop new adjacent projects at Alexandria Center® at Kendall Square. Since then, this property has served as a

reliable asset, providing primarily office space to our tenants. However, given the low occupancy and the significant reinvestment required for upgrades, we plan to recycle the capital generated by the disposition into our development and

redevelopment pipeline.

(4)Represents properties that were 65% occupied as of September 30, 2024, with 26% of the aggregate RSF scheduled to expire by June 30, 2025.

(5)Represents the sale of land parcels.

(6)Represents 100% of the contractual sales price. We held a 50% interest in this property through a consolidated real estate joint venture, and our share of the sales price and gain on real estate is $15.5 million and $3.2 million, respectively.

(7)Represents the disposition of an unconsolidated real estate joint venture for which we recognized a gain on sale of real estate of $3.3 million, which is classified as equity in earnings of unconsolidated real estate joint ventures in our

consolidated statement of operations. Refer to Note 4 – “Consolidated and unconsolidated real estate joint ventures” to our consolidated financial statements in Item 15 for additional information.

(8)Refer to footnotes 6 and 7.

New Class A/A+ development and redevelopment properties

pipelinepage.jpg

ALEXANDRIA’S FUTURE GROWTH IN

ANNUAL NET OPERATING INCOME FROM

DEVELOPMENT AND REDEVELOPMENT DELIVERIES

$395 MILLION

Placed Into Service

Expected to Be Placed Into Service

20244Q24
$118M$55M
1.5M RSF602,593 RSF
98% Occupied
20251Q26**–**2Q28
$83M$312M
89% Leased/Negotiating
Aggregating 4.4M RSF

(1)

(2)

(3)

Refer to “Net operating income” under “Definitions and reconciliations” in Item 7 for additional details including its reconciliation from the most directly comparable financial measures presented in accordance with GAAP.

(1)Our share of incremental annual net operating income from development and redevelopment projects expected to be placed into service primarily commencing from 1Q25 through 2Q28 is projected to be $334 million.

(2)Includes (i) 461,101 RSF that is expected to stabilize through 2025 and is 89% leased/negotiating and (ii) expected partial deliveries through 4Q25 from projects expected to stabilize in 2026 and beyond. Refer to the initial and stabilized

occupancy years under “New Class A/A+ development and redevelopment properties: current projects” in Item 2 for additional details.

(3)Represents the leased/negotiating percentage of development and redevelopment projects that are expected to stabilize during 2025.

New Class A/A+ development and redevelopment properties: recent deliveries

500 North Beacon Street and 4 Kingsbury Avenue**(1)**201 Brookline Avenue840 Winter Street
Greater Boston/ Cambridge/Inner SuburbsGreater Boston/FenwayGreater Boston/Route 128
211,574 RSF512,749 RSF139,984 RSF
100% Occupancy98% Occupancy100% Occupancy
arsenalphaseii.jpg201 Brookline v2.jpgwinter840.jpg
10935, 10945, and 10955 Alexandria Way**(2)**4155 Campus Point Court9808 Medical Center Drive
San Diego/Torrey PinesSan Diego/ University Town CenterMaryland/Rockville
93,492 RSF171,102 RSF95,061 RSF
100% Occupancy100% Occupancy69% Occupancy
alexandriawayOAS.jpgcampuspoint4155.jpgmcd9808.jpg

(1)Image represents 500 North Beacon Street on The Arsenal on the Charles Megacampus.

(2)Image represents 10955 Alexandria Way on the One Alexandria Square Megacampus.

New Class A/A+ development and redevelopment properties: recent deliveries (continued)

The following table presents development and redevelopment of new Class A/A+ projects placed into service during the year ended December 31, 2024 (dollars in thousands):

Incremental Annual Net Operating Income Generated From 2024 Deliveries

Aggregated $118 Million, Including $55 Million in 4Q24

Property/Market/Submarket4Q24 Delivery Date**(1)**Our Ownership InterestRSF Placed in ServiceOccupancy Percentage**(2)**Total ProjectUnlevered Yields
Prior to 1/1/241Q242Q243Q244Q24TotalInitial StabilizedInitial Stabilized (Cash Basis)
RSFInvestment
Development projects
99 Coolidge Avenue/Greater Boston/ Cambridge/Inner SuburbsN/A75.0%43,56872,846———116,414100%320,809$468,0007.1%7.0%
500 North Beacon Street and 4 Kingsbury Avenue/Greater Boston/Cambridge/Inner Suburbs11/1/24100%—100,62437,913—73,037211,574100%248,018427,0006.25.5
201 Brookline Avenue/Greater Boston/ Fenway10/30/2499.0%451,967———60,782512,74998%512,749787,0007.36.6
10935, 10945, and 10955 Alexandria Way/ San Diego/Torrey Pines11/1/24100%————93,49293,492100%334,996503,0006.25.8
4155 Campus Point Court/San Diego/ University Town Center11/7/2455.0%————171,102171,102100%171,102184,0008.06.4
1150 Eastlake Avenue East/Seattle/Lake UnionN/A100%278,282—2,07931,270—311,631100%311,631442,0006.66.7
9810 Darnestown Road/Maryland/RockvilleN/A100%——195,435——195,435100%195,435135,0007.16.2
9820 Darnestown Road/Maryland/RockvilleN/A100%———250,000—250,000100%250,000177,0008.75.6
9808 Medical Center Drive/Maryland/ Rockville12/31/24100%26,460—25,65513,05629,89095,06169%95,061114,0005.45.4
Redevelopment projects
840 Winter Street/Greater Boston/Route 12811/22/24100%————139,984139,984100%168,214224,0007.9(3)6.7(3)
651 Gateway Boulevard/San Francisco Bay Area/South San FranciscoN/A50.0%—44,652—22,365—67,017100%326,706487,0005.05.1
Alexandria Center® for Advanced Technologies – Monte Villa Parkway/ Seattle/Bothell12/31/24100%65,086115,598——34,306214,99090%460,934216,0006.36.2
CanadaN/A100%44,8629,72523,900——78,487100%250,790113,0006.46.3
Weighted average/total11/7/24910,225343,445284,982316,691602,5932,457,9363,646,445$4,277,0006.7%6.2%

(1)Represents the average delivery date for deliveries that occurred during the three months ended December 31, 2024, weighted by annual rental revenue.

(2)Occupancy relates to total operating RSF placed in service as of the most recent delivery.

(3)Represents initial stabilized yields upon completion and delivery of the project during the three months ended December 31, 2024. However, we are actively negotiating with our existing anchor tenant to potentially relocate them to another

Alexandria property to accommodate their future growth, and if this occurs, our future returns on this asset could change as we backfill this building with a new tenant.

New Class A/A+ development and redevelopment properties: current projects

99 Coolidge Avenue500 North Beacon Street and 4 Kingsbury Avenue**(1)**311 Arsenal Street401 Park Drive
Greater Boston/ Cambridge/Inner SuburbsGreater Boston/ Cambridge/Inner SuburbsGreater Boston/ Cambridge/Inner SuburbsGreater Boston/Fenway
204,395 RSF36,444 RSF308,446 RSF137,675 RSF
62% Leased/Negotiating92% Leased/Negotiating21% Leased/Negotiating—% Leased/Negotiating
99Coolidge.jpgarsenalphaseii.jpgarsenal311.jpgparkdrive401v2.jpg
421 Park Drive40, 50, and 60 Sylvan Road1450 Owens Street651 Gateway Boulevard
Greater Boston/FenwayGreater Boston/Route 128San Francisco Bay Area/ Mission BaySan Francisco Bay Area/ South San Francisco
392,011 RSF596,064 RSF109,435 RSF259,689 RSF
13% Leased/Negotiating31% Leased/Negotiating(2)—% Leased/Negotiating(3)21% Leased/Negotiating
parkdrive421.jpg60 Sylvan.jpgowens1450.jpggateway651.jpg

(1)Image represents 500 North Beacon Street on The Arsenal on the Charles Megacampus.

(2)Image represents 60 Sylvan Road on the Alexandria Center® for Life Science – Waltham Megacampus. The project is expected to capture demand in our Route 128 submarket.

(3)Image represents a multi-tenant project expanding our existing Alexandria Center® for Science and Technology – Mission Bay Megacampus, where our joint venture partner will fund 100% of the construction cost until it attains an ownership

interest of 75%, after which it will contribute its respective share of additional capital. Additionally, during the three months ended December 31, 2024, we executed a letter of intent with a biomedical institution for the sale of a condominium

interest aggregating 103,361 RSF, or approximately 49% of the development project. We expect to complete the transaction in 2025. Accordingly, we adjusted the development project RSF and its related book value to reflect 109,435 RSF,

with our ownership share expected to be 25% at completion of the project.

New Class A/A+ development and redevelopment properties: current projects (continued)

230 Harriet Tubman Way269 East Grand Avenue10935, 10945, and 10955 Alexandria Way**(1)**4135 Campus Point Court
San Francisco Bay Area/ South San FranciscoSan Francisco Bay Area/ South San FranciscoSan Diego/Torrey PinesSan Diego/ University Town Center
285,346 RSF107,250 RSF241,504 RSF426,927 RSF
100% Leased—% Leased/Negotiating100% Leased100% Leased
harriettubman.jpg269EGrand.jpgalexandriawayOAS.jpgCampuspoint4135.jpg
10075 Barnes Canyon Road701 Dexter Avenue North8800 Technology Forest Place
San Diego/Sorrento MesaSeattle/Lake UnionTexas/Greater Houston
253,079 RSF227,577 RSF73,298 RSF
70% Leased/Negotiating—% Leased/Negotiating41% Leased/Negotiating
barnescanyon10075.jpg701Dexter.jpgTechforest8800v3.jpg

(1)Image represents 10955 Alexandria Way on the One Alexandria Square Megacampus.

New Class A/A+ development and redevelopment properties: current projects (continued)

The following tables set forth a summary of our new Class A/A+ development and redevelopment properties under construction as of December 31, 2024 (dollars in thousands):

Property/Market/SubmarketSquare FootagePercentageOccupancy**(1)**
Dev/RedevIn ServiceCIPTotalLeasedLeased/ NegotiatingInitialStabilized
Under construction
2025 stabilization
500 North Beacon Street and 4 Kingsbury Avenue/Greater Boston/ Cambridge/Inner SuburbsDev211,57436,444248,01892%92%1Q242025
230 Harriet Tubman Way/San Francisco Bay Area/South San FranciscoDev—285,346285,3461001001Q251Q25
CanadaRedev111,479139,311250,79073753Q232025
323,053461,101784,1548989
2026 and beyond stabilization
One Hampshire Street/Greater Boston/CambridgeRedev—104,956104,956——20272028
311 Arsenal Street/Greater Boston/Cambridge/Inner SuburbsRedev82,216(2)308,446390,662212120272027
99 Coolidge Avenue/Greater Boston/Cambridge/Inner SuburbsDev116,414204,395320,80940624Q232026
401 Park Drive/Greater Boston/Fenway(3)Redev—137,675137,675——20262026
421 Park Drive/Greater Boston/FenwayDev—392,011392,011131320262027
40, 50, and 60 Sylvan Road/Greater Boston/Route 128Redev—596,064596,064313120262027
Other/Greater BostonRedev—453,869453,869——(4)20272027
1450 Owens Street/San Francisco Bay Area/Mission BayDev—109,435109,435——(5)20262026
651 Gateway Boulevard/San Francisco Bay Area/South San FranciscoRedev67,017259,689326,70621211Q242027
269 East Grand Avenue/San Francisco Bay Area/South San FranciscoRedev—107,250107,250——20262027
10935, 10945, and 10955 Alexandria Way/San Diego/Torrey PinesDev93,492241,504334,9961001004Q242026
4135 Campus Point Court/San Diego/University Town CenterDev—426,927426,92710010020262026
10075 Barnes Canyon Road/San Diego/Sorrento MesaDev—253,079253,079707020252026
701 Dexter Avenue North/Seattle/Lake UnionDev—227,577227,577——20262027
8800 Technology Forest Place/Texas/Greater HoustonRedev50,09473,298123,39241412Q232026
409,2333,896,1754,305,4083537
732,2864,357,2765,089,56243%45%
(1)Initial occupancy dates are subject to leasing and/or market conditions. Stabilized occupancy may vary depending on single tenancy versus multi-tenancy. Multi-tenant projects may increase in occupancy over a period of time. (2)We expect to redevelop an additional 25,312 RSF of space occupied as of December 31, 2024 into laboratory space upon expiration of the existing leases through the second half of 2025. Refer to “Investments in real estate” under “Definitions and reconciliations” in Item 7 for additional information. (3)During the three months ended December 31, 2024, we shifted the strategy of our 401 Park Drive redevelopment project to focus on the largest, most significant phase of the project. This phase aggregated 137,675 RSF and is expected to initially deliver and stabilize in 2026. Accordingly, we placed the less significant portion of the project that aggregated 22,284 RSF back into operations. (4)Represents a project focused on demand from our existing tenants in our adjacent properties/campuses that will address demand from other non-Alexandria properties/campuses. (5)Represents a multi-tenant project expanding our existing Alexandria Center® for Science and Technology – Mission Bay Megacampus, where our joint venture partner will fund 100% of the construction cost until it attains an ownership interest of 75%, after which it will contribute its respective share of additional capital. During the three months ended December 31, 2024, we executed a letter of intent with a biomedical institution for the sale of a condominium interest aggregating 103,361 RSF, or approximately 49% of the development project, with the transaction expected to close in 2025. Accordingly, we adjusted the development project RSF and its related book value to reflect 109,435 RSF, with our ownership share expected to be 25% at completion of the project.

New Class A/A+ development and redevelopment properties: current projects (continued)

Our Ownership InterestAt 100%Unlevered Yields
Property/Market/SubmarketIn ServiceCIPCost to CompleteTotal at CompletionInitial StabilizedInitial Stabilized (Cash Basis)
Under construction
2025 stabilization
500 North Beacon Street and 4 Kingsbury Avenue/Greater Boston/ Cambridge/Inner Suburbs100%$378,021$37,026$11,953$427,0006.2%5.5%
230 Harriet Tubman Way/San Francisco Bay Area/South San Francisco48.2%—404,591105,409510,0007.4%6.4%
Canada100%50,23551,59611,169113,0006.4%6.3%
428,256493,213
2026 and beyond stabilization(1)
One Hampshire Street/Greater Boston/Cambridge100%—164,957TBD
311 Arsenal Street/Greater Boston/Cambridge/Inner Suburbs100%60,649240,342
99 Coolidge Avenue/Greater Boston/Cambridge/Inner Suburbs75.0%136,635196,917134,448468,0007.1%7.0%
401 Park Drive/Greater Boston/Fenway100%—151,301TBD
421 Park Drive/Greater Boston/Fenway99.8%—463,079
40, 50, and 60 Sylvan Road/Greater Boston/Route 128100%—449,484
Other/Greater Boston100%—151,464
1450 Owens Street/San Francisco Bay Area/Mission Bay25.1%—121,957
651 Gateway Boulevard/San Francisco Bay Area/South San Francisco50.0%87,376258,708140,916487,0005.0%5.1%
269 East Grand Avenue/San Francisco Bay Area/South San Francisco100%—66,184TBD
10935, 10945, and 10955 Alexandria Way/San Diego/Torrey Pines100%100,944323,99378,063503,0006.2%5.8%
4135 Campus Point Court/San Diego/University Town Center55.0%—347,039176,961524,0006.6%6.2%
10075 Barnes Canyon Road/San Diego/Sorrento Mesa50.0%—183,733137,267321,0005.5%5.7%
701 Dexter Avenue North/Seattle/Lake Union100%—234,908TBD
8800 Technology Forest Place/Texas/Greater Houston100%59,79446,2785,928112,0006.3%6.0%
445,3983,400,344
$873,654$3,893,557$2,740,000(2)$7,510,000(2)
Our share of investment(2)(3)$800,000$3,180,000$2,400,000$6,380,000
Refer to “Initial stabilized yield (unlevered)” under “Definitions and reconciliations” in Item 7 for additional information. (1)We expect to provide total estimated costs and related yields for each project with estimated stabilization in 2026 and beyond over the next several quarters. (2)Represents dollar amount rounded to the nearest $10 million and includes preliminary estimated amounts for projects listed as TBD. (3)Represents our share of investment based on our ownership percentage upon completion of development or redevelopment projects.

New Class A/A+ development and redevelopment properties: summary of pipeline

68% of Our Total Development and Redevelopment Pipeline RSF Is Within Our Megacampus™ Ecosystems

The following table summarizes the key information for all our development and redevelopment projects in North America as of December 31, 2024 (dollars in thousands):

Market Property/SubmarketOur Ownership InterestBook ValueSquare Footage
Development and RedevelopmentTotal**(1)**
Future Opportunities Subject to Market Conditions and Leasing
Under ConstructionPriority AnticipatedFuture
Greater Boston
Megacampus: Alexandria Center**®** at One Kendall Square/Cambridge100%$164,957104,956——104,956
One Hampshire Street
Megacampus: The Arsenal on the Charles/Cambridge/Inner Suburbs100%288,993344,89025,31234,157404,359
311 Arsenal Street, 500 North Beacon Street, and 4 Kingsbury Avenue
Megacampus: 480 Arsenal Way and 446, 458, 500, and 550 Arsenal Street, and 99 Coolidge Avenue/Cambridge/Inner Suburbs(2)285,870204,395—902,0001,106,395
446, 458, 500, and 550 Arsenal Street, and 99 Coolidge Avenue
Megacampus: Alexandria Center**®** for Life Science – Fenway/Fenway(3)614,380529,686——529,686
401 and 421 Park Drive
Megacampus: Alexandria Center**®** for Life Science – Waltham/Route 128100%512,996596,064—515,0001,111,064
40, 50, and 60 Sylvan Road, and 35 Gatehouse Drive
Megacampus: Alexandria Center**®** at Kendall Square/Cambridge100%204,128——174,500174,500
100 Edwin H. Land Boulevard
Megacampus: Alexandria Technology Square**®****/Cambridge**100%7,907——100,000100,000
Megacampus: 285, 299, 307, and 345 Dorchester Avenue/Seaport Innovation District60.0%288,527——1,040,0001,040,000
10 Necco Street/Seaport Innovation District100%105,106——175,000175,000
215 Presidential Way/Route 128100%6,816——112,000112,000
Other development and redevelopment projects(4)405,145453,869—1,365,4961,819,365
$2,884,8252,233,86025,3124,418,1536,677,325
Refer to “Megacampus” under “Definitions and reconciliations” in Item 7 for additional information. (1)Represents total square footage upon completion of development or redevelopment of one or more new Class A/A+ properties. Square footage presented includes the RSF of buildings currently in operation at properties that also have future development or redevelopment opportunities. Upon expiration of existing in-place leases, we have the intent to demolish or redevelop the existing property subject to market conditions and leasing. Refer to “Investments in real estate” under “Definitions and reconciliations” in Item 7 for additional information, including development and redevelopment square feet currently included in rental properties. (2)We have a 75.0% interest in 99 Coolidge Avenue aggregating 204,395 RSF and a 100% interest in 446, 458, 500, and 550 Arsenal Street aggregating 902,000 RSF. (3)We have a 100% interest in 401 Park Drive aggregating 137,675 RSF and a 99.8% interest in 421 Park Drive aggregating 392,011 RSF. (4)Includes a property in which we own a partial interest through a real estate joint venture.

New Class A/A+ development and redevelopment properties: summary of pipeline (continued)

Market Property/SubmarketOur Ownership InterestBook ValueSquare Footage
Development and RedevelopmentTotal**(1)**
Future Opportunities Subject to Market Conditions and Leasing
Under ConstructionPriority AnticipatedFuture
San Francisco Bay Area
Megacampus: Alexandria Center**®** for Science and Technology – Mission Bay/ Mission Bay25.1%$121,957(2)109,435(2)——109,435
1450 Owens Street
Alexandria Center® for Life Science – Millbrae/South San Francisco48.2%568,776285,346198,188150,213633,747
230 Harriet Tubman Way, 201 and 231 Adrian Road, and 6 and 30 Rollins Road
Megacampus: Alexandria Technology Center**®** – Gateway/South San Francisco50.0%285,334259,689—291,000550,689
651 Gateway Boulevard
Megacampus: Alexandria Center**®** for Advanced Technologies – South San Francisco/South San Francisco100%72,839107,250—90,000197,250
211*(3)* and 269 East Grand Avenue
Megacampus: Alexandria Center**®** for Advanced Technologies – Tanforan/South San Francisco100%406,586——1,930,0001,930,000
1122, 1150, and 1178 El Camino Real
Megacampus: Alexandria Center**®** for Life Science – San Carlos/Greater Stanford100%455,849——1,497,8301,497,830
960 Industrial Road, 987 and 1075 Commercial Street, and 888 Bransten Road
3825 and 3875 Fabian Way/Greater Stanford100%156,602——478,000478,000
2100, 2200, 2300, and 2400 Geng Road/Greater Stanford100%37,264——240,000240,000
Megacampus: 88 Bluxome Street/SoMa100%397,952——1,070,9251,070,925
Other development and redevelopment projects100%———56,92456,924
$2,503,159761,720198,1885,804,8926,764,800
Refer to “Megacampus” under “Definitions and reconciliations” in Item 7 for additional information. (1)Represents total square footage upon completion of development or redevelopment of one or more new Class A/A+ properties. Square footage presented includes the RSF of buildings currently in operation at properties that also have future development or redevelopment opportunities. Upon expiration of existing in-place leases, we have the intent to demolish or redevelop the existing property subject to market conditions and leasing. Refer to “Investments in real estate” under “Definitions and reconciliations” in Item 7 for additional information, including development and redevelopment square feet currently included in rental properties. (2)During the three months ended December 31, 2024, we executed a letter of intent with a biomedical institution for the sale of a condominium interest aggregating 103,361 RSF, or approximately 49% of the development project, with the transaction expected to close in 2025. Accordingly, we adjusted the development project RSF and its related book value to reflect 109,435 RSF, with our ownership share expected to be 25% at completion of the project. (3)We own a partial interest in this property through a real estate joint venture. Refer to Note 4 – “Consolidated and unconsolidated real estate joint ventures” to our consolidated financial statements in Item 15 for additional details.

New Class A/A+ development and redevelopment properties: summary of pipeline (continued)

Market Property/SubmarketOur Ownership InterestBook ValueSquare Footage
Development and RedevelopmentTotal**(1)**
Future Opportunities Subject to Market Conditions and Leasing
Under ConstructionPriority AnticipatedFuture
San Diego
Megacampus: One Alexandria Square/Torrey Pines100%$382,913241,504—125,280366,784
10935 and 10945 Alexandria Way and 10975 and 10995 Torreyana Road
Megacampus: Campus Point by Alexandria/University Town Center55.0%492,221426,927333,414634,0431,394,384
10010*(2), 10140(2)**, 10210, and 10260 Campus Point Drive and 4135, 4161, 4165, and* 4224 Campus Point Court
Megacampus: SD Tech by Alexandria/Sorrento Mesa50.0%346,929253,079250,000243,845746,924
9805 Scranton Road and 10075 Barnes Canyon Road
11255 and 11355 North Torrey Pines Road/Torrey Pines100%153,104—153,00062,000215,000
Megacampus: 5200 Illumina Way/University Town Center51.0%17,443——451,832451,832
9625 Towne Centre Drive/University Town Center30.0%837——100,000100,000
Megacampus: Sequence District by Alexandria/Sorrento Mesa100%46,323——1,798,9151,798,915
6260, 6290, 6310, 6340, 6350, and 6450 Sequence Drive
Scripps Science Park by Alexandria/Sorrento Mesa100%42,417——154,308154,308
10256 and 10260 Meanley Drive
4075 Sorrento Valley Boulevard/Sorrento Valley100%19,130——144,000144,000
Other development and redevelopment projects(3)76,843——475,000475,000
$1,578,160921,510736,4144,189,2235,847,147
Refer to “Megacampus” under “Definitions and reconciliations” in Item 7 for additional information. (1)Represents total square footage upon completion of development or redevelopment of one or more new Class A/A+ properties. Square footage presented includes RSF of buildings currently in operation at properties that also have inherent future development or redevelopment opportunities. Upon expiration of existing in-place leases, we have the intent to demolish or redevelop the existing property subject to market conditions and leasing. Refer to “Investments in real estate” under “Definitions and reconciliations” in Item 7 for additional information, including development and redevelopment square feet currently included in rental properties. (2)We have a 100% interest in this property. (3)Includes a property in which we own a partial interest through a real estate joint venture.

New Class A/A+ development and redevelopment properties: summary of pipeline (continued)

Market Property/SubmarketOur Ownership InterestBook ValueSquare Footage
Development and RedevelopmentTotal**(1)**
Future Opportunities Subject to Market Conditions and Leasing
Under ConstructionPriority AnticipatedFuture
Seattle
Megacampus: Alexandria Center**®** for Life Science – South Lake Union/Lake Union(2)$516,743227,577869,000188,4001,284,977
601 and 701 Dexter Avenue North and 800 Mercer Street
1010 4th Avenue South/SoDo100%59,996——544,825544,825
410 West Harrison Street/Elliott Bay100%———91,00091,000
Megacampus: Alexandria Center**®** for Advanced Technologies – Canyon Park/ Bothell100%18,066——230,000230,000
21660 20th Avenue Southeast
Other development and redevelopment projects100%144,644——706,087706,087
739,449227,577869,0001,760,3122,856,889
Maryland
Megacampus: Alexandria Center**®** for Life Science – Shady Grove/Rockville100%22,593——296,000296,000
9830 Darnestown Road
22,593——296,000296,000
Research Triangle
Megacampus: Alexandria Center**®** for Advanced Technologies and Agtech – Research Triangle/Research Triangle100%106,906—180,000990,0001,170,000
4 and 12 Davis Drive
Megacampus: Alexandria Center**®** for Life Science – Durham/Research Triangle100%158,277——2,060,0002,060,000
Megacampus: Alexandria Center**®** for NextGen Medicines/Research Triangle100%109,368——1,055,0001,055,000
3029 East Cornwallis Road
Megacampus: Alexandria Center**®** for Sustainable Technologies/Research Triangle100%53,941——750,000750,000
120 TW Alexander Drive, 2752 East NC Highway 54, and 10 South Triangle Drive
100 Capitola Drive/Research Triangle100%———65,96565,965
Other development and redevelopment projects100%4,185——76,26276,262
$432,677—180,0004,997,2275,177,227
Refer to “Megacampus” under “Definitions and reconciliations” in Item 7 for additional information. (1)Represents total square footage upon completion of development or redevelopment of one or more new Class A/A+ properties. Square footage presented includes the RSF of buildings currently in operation at properties that also have inherent future development or redevelopment opportunities. Upon expiration of existing in-place leases, we have the intent to demolish or redevelop the existing property. Refer to “Investments in real estate” under “Definitions and reconciliations” in Item 7 for additional information, including development and redevelopment square feet currently included in rental properties. (2)We have a 100% interest in 601 and 701 Dexter Avenue North aggregating 415,977 RSF and a 60% interest in the priority anticipated development project at 800 Mercer Street aggregating 869,000 RSF.

New Class A/A+ development and redevelopment properties: summary of pipeline (continued)

Market Property/SubmarketOur Ownership InterestBook ValueSquare Footage
Development and RedevelopmentTotal**(1)**
Future Opportunities Subject to Market Conditions and Leasing
Under ConstructionPriority AnticipatedFuture
New York City
Megacampus: Alexandria Center**®** for Life Science – New York City/New York City100%$168,423——550,000(2)550,000
168,423——550,000550,000
Texas
Alexandria Center® for Advanced Technologies at The Woodlands/Greater Houston100%49,11873,298—116,405189,703
8800 Technology Forest Place
1001 Trinity Street and 1020 Red River Street/Austin100%10,533—126,034123,976250,010
Other development and redevelopment projects100%56,798——344,000344,000
116,44973,298126,034584,381783,713
Canada100%51,596139,311—371,743511,054
Other development and redevelopment projects100%121,396——724,349724,349
Total pipeline as of December 31, 2024, excluding properties held for sale8,618,7274,357,2762,134,94823,696,28030,188,504
Properties held for sale237,739——2,390,8562,390,856
Total pipeline as of December 31, 2024$8,856,466(3)4,357,2762,134,94826,087,13632,579,360

Refer to “Megacampus” under “Definitions and reconciliations” in Item 7 for additional information.

(1)Total square footage includes 3,056,674 RSF of buildings currently in operation that we expect to demolish or redevelop and commence future construction subject to market conditions and leasing. Refer to “Investments in real estate”

under “Definitions and reconciliations” in Item 7 for additional information, including development and redevelopment square feet currently included in rental properties.

(2)During the three months ended September 30, 2024, we filed a lawsuit against the New York City Health + Hospitals Corporation and the New York City Economic Development Corporation for fraud and breach of contract concerning our

option to ground lease a land parcel to develop a future world-class life science building within the Alexandria Center® for Life Science – New York City Megacampus. Refer to “Legal proceedings” in Item 3 for additional details.

(3)Includes $3.9 billion of projects that are currently under construction.

Previous: Item 1C. CYBERSECURITY · Next: Item 3. LEGAL PROCEEDINGS