Item 6. EXHIBITS
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Item 6. EXHIBITS
Exhibits (listed by number corresponding to the Exhibit Table of Item 601 in Regulation S-K).
| Exhibit No. | Description | |||||||
| 31a. | Section 302 Certification Letter (filed herewith). | |||||||
| 31b. | Section 302 Certification Letter (filed herewith). | |||||||
| 32a. | Section 906 Certification Letter (furnished herewith). | |||||||
| 32b. | Section 906 Certification Letter (furnished herewith). | |||||||
| 101.INS | Inline XBRL Instance Document - the instance document does not appear in the Interactive Data File because its XBRL tags are embedded within the Inline XBRL document. | |||||||
| 101.SCH | Inline XBRL Taxonomy Extension Schema Document. | |||||||
| 101.CAL | Inline XBRL Taxonomy Extension Calculation Linkbase Document. | |||||||
| 101.DEF | Inline XBRL Taxonomy Extension Definition Linkbase Document. | |||||||
| 101.LAB | Inline XBRL Taxonomy Extension Label Linkbase Document. | |||||||
| 101.PRE | Inline XBRL Taxonomy Extension Presentation Linkbase Document. | |||||||
| 104 | Cover Page Interactive Data File (formatted as Inline XBRL and contained in Exhibit 101). |
- Indicates, in this Quarterly Report on Form 10-Q, brand names of products, which are registered trademarks not solely owned by the Company or its subsidiaries. Gleevec is a trademark of Novartis AG; Keytruda is a trademark of Merck & Co., Inc., Rahway, NJ, USA; Plavix is a trademark of Sanofi; and Tecentriq is a trademark of Genentech, Inc. Brand names of products that are in all italicized letters, without an asterisk, are registered trademarks of BMS and/or one of its subsidiaries.
SUMMARY OF ABBREVIATED TERMS
Bristol-Myers Squibb Company and its consolidated subsidiaries may be referred to as Bristol Myers Squibb, BMS, the Company, we, our or us in this Quarterly Report on Form 10-Q, unless the context otherwise indicates. Throughout this Quarterly Report on Form 10-Q we have used terms which are defined below:
| 2024 Form 10-K | Annual Report on Form 10-K for the fiscal year ended December 31, 2024 | MDS | myelodysplastic syndromes | ||||||||
| 2024 Senior Unsecured Notes | Aggregate principal amount of $13.0 billion of senior unsecured notes issued by BMS in February 2024 | Merck | Merck & Co. | ||||||||
| 2seventy bio | 2seventy bio, Inc. | Mirati | Mirati Therapeutics, Inc. | ||||||||
| aGVHD | acute graft-versus-host disease | MPM | malignant pleural mesothelioma | ||||||||
| ADC | antibody-drug conjugate | MSI-H | microsatellite instability-high | ||||||||
| ADP | adenosine diphosphate | MTA | Methylthioadenosine | ||||||||
| ANDA | Abbreviated New Drug Application | MZL | marginal zone lymphoma | ||||||||
| AOCI | Accumulated other comprehensive loss | NDA | New Drug Application | ||||||||
| AstraZeneca | AstraZeneca PLC | nHCM | Nonobstructive Hypertrophic Cardiomyopathy | ||||||||
| BCMA | B-cell maturation antigen-directed | NHL | Non-Hodgkin's Lymphoma | ||||||||
| BioArctic | BioArctic AB | NKT | natural killer T | ||||||||
| BioNTech | BioNTech SE | NSCLC | non-small cell lung cancer | ||||||||
| CAR-T | chimeric antigen receptor T-cell | NTRK | Neurotrophic Tropomyosin Receptor Kinase | ||||||||
| Celgene | Celgene Corporation | Nimbus | Nimbus Therapeutics | ||||||||
| CERCLA | U.S. Comprehensive Environmental Response, Compensation and Liability Act | NVAF | non-valvular atrial fibrillation | ||||||||
| CGDP | Coverage Gap Discount Program | OECD | Organization for Economic Co-operation and Development | ||||||||
| CHMP | Committee for Medicinal Products for Human Use | oHCM | Obstructive Hypertrophic Cardiomyopathy | ||||||||
| CLL | Chronic Lymphocytic Leukemia | Ono | Ono Pharmaceutical Co., Ltd | ||||||||
| CML | chronic myeloid leukemia | ORR | overall response rate | ||||||||
| CRC | colorectal carcinoma | PD-1 | programmed cell death protein 1 | ||||||||
| CTLA4 | Cytotoxic T-lymphocyte Antigen-4 | PD-L1 | programmed death-ligand 1 | ||||||||
| CVR | Contingent value right | PDUFA | Prescription Drug User Fee Act | ||||||||
| DLBCL | Diffuse Large B-cell Lymphoma | PE | pulmonary embolism | ||||||||
| dMMR | mismatch repair deficient | Philochem | Philochem AG | ||||||||
| DVT | deep vein thrombosis | PRMT5 | protein arginine methyltransferase 5 | ||||||||
| EC | European Commission | PsA | psoriatic arthritis | ||||||||
| Eisai | Eisai Co., Ltd. | Quarterly Report on Form 10-Q | Quarterly Report on Form 10-Q for the quarter ended June 30, 2025 | ||||||||
| EMA | European Medicines Agency | R&D | research and development | ||||||||
| EPS | earnings per share | RA | rheumatoid arthritis | ||||||||
| ES-SCLC | extensive stage small cell lung cancer | RayzeBio | RayzeBio, Inc. | ||||||||
| EU | European Union | RCC | renal cell carcinoma | ||||||||
| Exchange Act | the Securities Exchange Act of 1934 | RDFV | readily determinable fair values | ||||||||
| FASB | Financial Accounting Standards Board | REMS | risk evaluation and mitigation strategy | ||||||||
| FDA | U.S. Food and Drug Administration | Roche | F. Hoffman-La Roche & Co. | ||||||||
| FL | follicular lymphoma | RPT | radiopharmaceutical therapeutics | ||||||||
| GAAP | generally accepted accounting principles | RS | ring sideroblast | ||||||||
| GTN | gross-to-net | Sanofi | Sanofi S.A. | ||||||||
| HCC | hepatocellular carcinoma | SEC | U.S. Securities and Exchange Commission | ||||||||
| HCM | hypertrophic cardiomyopathy | SLL | Small Lymphocytic Lymphoma | ||||||||
| HHS | Health and Human Services | SPC | Supplementary Protection Certificate | ||||||||
| IPRD | in-process research and development | SystImmune | SystImmune, Inc. | ||||||||
| IRA | Inflation Reduction Act of 2022 | TCJA | Tax Cuts and Jobs Act of 2017 | ||||||||
| IRS | Internal Revenue Service | TNBC | triple negative breast cancer | ||||||||
| JIA | juvenile idiopathic arthritis | UC | ulcerative colitis | ||||||||
| Karuna | Karuna Therapeutics, Inc. | UK | United Kingdom | ||||||||
| KRAS | Kirsten rat sarcoma | U.S. | United States | ||||||||
| LBCL | Large B-cell Lymphoma | VAT | value added tax | ||||||||
| MCL | mantle cell lymphoma | VEGF-A | Vascular endothelial growth factor A |
SIGNATURES
Pursuant to the requirements of the Securities Exchange Act of 1934, the Registrant has duly caused this report to be signed on its behalf by the undersigned thereunto duly authorized.
| BRISTOL-MYERS SQUIBB COMPANY (REGISTRANT) | |||||||||||
| Date: | July 31, 2025 | By: | /s/ Christopher Boerner, Ph.D. | ||||||||
| Christopher Boerner, Ph. D. Chair of the Board and Chief Executive Officer | |||||||||||
| Date: | July 31, 2025 | By: | /s/ David V. Elkins | ||||||||
| David V. Elkins Chief Financial Officer |
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