Item 6. Exhibits

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Item 6. Exhibits


Exhibit designation	Nature of exhibit	Previously filed as exhibit to



Officer certifications:
31*	Rule 13a-14(a) Certifications
32*	Section 1350 Certifications

Other exhibits:
22.1	List of Subsidiary Issuers and Guarantors

Interactive data files:
101*	The following financial information from CSX Corporation's Quarterly Report on Form 10-Q for the quarter ended March 31, 2022 filed with the SEC on April 20, 2022, formatted in inline XBRL includes: (i) consolidated income statements for the quarters ended March 31, 2022 and March 31, 2021, (ii) condensed consolidated comprehensive income statements for the quarters ended March 31, 2022 and March 31, 2021, (iii) consolidated balance sheets at March 31, 2022 and December 31, 2021, (iv) consolidated cash flow statements for the three months ended March 31, 2022 and March 31, 2021, (v) consolidated statement of changes in shareholders' equity for the quarters ended March 31, 2022 and March 31, 2021, and (vi) the notes to consolidated financial statements.
104	Cover Page Interactive Data File (embedded within the Inline XBRL document contained in Exhibit 101)




* Filed herewith

CSX Q1 2022 Form 10-Q p.43

CSX CORPORATION

PART II

SIGNATURE

Pursuant to the requirements of the Securities Exchange Act of 1934, the registrant has duly caused this report to be signed on its behalf by the undersigned thereunto duly authorized.

CSX CORPORATION

(Registrant)

By: /s/ ANGELA C. WILLIAMS

Angela C. Williams

Vice President and

Chief Accounting Officer

(Principal Accounting Officer)

Dated: April 20, 2022

CSX Q1 2022 Form 10-Q p.44

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