Item 5. Other Information

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Item 5. Other Information

As disclosed in the table below, during the three months ended June 30, 2023, certain of our directors and/or executive officers adopted plans for trading arrangements intended to satisfy the affirmative defense conditions of Rule 10b5-1(c) of the Exchange Act.

NamePositionDate of Plan AdoptionScheduled End Date of Trading Arrangement**(a)**Total Number of Securities to Be Sold Under the Plan
Bonnie L. Bassler, Ph.D.Director5/11/20237/31/20243,969
Andrew J. Murphy, Ph.D.Executive Vice President, Research5/9/202312/31/202480,000
Huda Y. Zoghbi, M.D.Director5/5/20232/10/20242,117
(a) In each case, the trading arrangement may expire on an earlier date if and when all transactions under the arrangement are completed.

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