Item 5. Other Information

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Item 5. Other Information

As disclosed in the table below, during the three months ended March 31, 2024, certain of our directors and/or executive officers adopted plans for trading arrangements intended to satisfy the affirmative defense conditions of Rule 10b5-1(c) of the Exchange Act.


Name	Position	Date of Plan Adoption	Scheduled End Date of Trading Arrangement(a)	Total Number of Securities to Be Sold Under the Plan
Bonnie L. Bassler, Ph.D.	Director	2/27/2024	4/30/2025	3,851
Michael S. Brown, M.D.	Director	2/26/2024	8/31/2024	2,707
Joseph J. LaRosa	Executive Vice President, General Counsel and Secretary	2/16/2024	2/10/2025	5,191
Marion McCourt	Executive Vice President, Commercial	2/13/2024	5/31/2025	8,122
Leonard S. Schleifer, M.D., Ph.D.	Board co-Chair, President and Chief Executive Officer	2/5/2024	8/5/2025	229,204
George D. Yancopoulos, M.D., Ph.D.	Board co-Chair, President and Chief Scientific Officer	2/14/2024	2/10/2025	100,000

(a) In each case, the trading arrangement may expire on an earlier date if and when all transactions under the arrangement are completed.

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