Item 5. Other Information

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Item 5. Other Information

As disclosed in the table below, during the three months ended March 31, 2025, certain of our directors and/or executive officers adopted plans for trading arrangements intended to satisfy the affirmative defense conditions of Rule 10b5-1(c) of the Exchange Act.

NamePositionDate of Plan AdoptionScheduled End Date of Trading Arrangement**(a)**Total Number of Securities to Be Sold Under the Plan
Joseph L. Goldstein, M.D.Director2/13/202511/30/20251,929
(a) The trading arrangement may expire on an earlier date if and when all transactions under the arrangement are completed

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