Item 16. FORM 10-K SUMMARY.
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Item 16. FORM 10-K SUMMARY.
None.
SIGNATURES
Pursuant to the requirements of Section 13 or 15(d) of the Securities Exchange Act of 1934, the Registrant has duly caused this Report to be signed on its behalf by the undersigned, thereunto duly authorized.
| BRISTOL-MYERS SQUIBB COMPANY (Registrant) | ||||||||
| By | /s/ GIOVANNI CAFORIO, M.D. | |||||||
| Giovanni Caforio, M.D. | ||||||||
| Chairman of the Board and Chief Executive Officer | ||||||||
| Date: February 14, 2023 |
Pursuant to the requirements of the Securities Exchange Act of 1934, this Report has been signed below by the following persons on behalf of the Registrant and in the capacities and on the dates indicated.
| Signature | Title | Date | ||||||||||||
| /s/ GIOVANNI CAFORIO, M.D. | Chairman of the Board and Chief Executive Officer | February 14, 2023 | ||||||||||||
| (Giovanni Caforio, M.D.) | (Principal Executive Officer) | |||||||||||||
| /s/ DAVID V. ELKINS | Chief Financial Officer | February 14, 2023 | ||||||||||||
| (David V. Elkins) | (Principal Financial Officer) | |||||||||||||
| /s/ SHARON GREENLEES | Senior Vice President and Corporate Controller | February 14, 2023 | ||||||||||||
| (Sharon Greenlees) | (Principal Accounting Officer) | |||||||||||||
| /s/ PETER J. ARDUINI | Director | February 14, 2023 | ||||||||||||
| (Peter J. Arduini) | ||||||||||||||
| /s/ DEEPAK L. BHATT. M.D. MPH | Director | February 14, 2023 | ||||||||||||
| (Deepak L. Bhatt, M.D. MPH) | ||||||||||||||
| /s/ JULIA A. HALLER, M.D. | Director | February 14, 2023 | ||||||||||||
| (Julia A. Haller, M.D.) | ||||||||||||||
| /s/ MANUEL HIDALGO MEDINA, M.D., Ph.D. | Director | February 14, 2023 | ||||||||||||
| (Manuel Hidalgo Medina, M.D., Ph.D.) | ||||||||||||||
| /s/ PAULA A. PRICE | Director | February 14, 2023 | ||||||||||||
| (Paula A. Price) | ||||||||||||||
| /s/ DERICA W. RICE | Director | February 14, 2023 | ||||||||||||
| (Derica W. Rice) | ||||||||||||||
| /s/ THEODORE R. SAMUELS | Director | February 14, 2023 | ||||||||||||
| (Theodore R. Samuels) | ||||||||||||||
| /s/ GERALD L. STORCH | Director | February 14, 2023 | ||||||||||||
| (Gerald L. Storch) | ||||||||||||||
| /s/ KAREN H. VOUSDEN, Ph.D. | Director | February 14, 2023 | ||||||||||||
| (Karen H. Vousden, Ph.D.) | ||||||||||||||
| /s/ PHYLLIS R. YALE | Director | February 14, 2023 | ||||||||||||
| (Phyllis R. Yale) |
SUMMARY OF ABBREVIATED TERMS
Bristol-Myers Squibb Company and its consolidated subsidiaries may be referred to as Bristol Myers Squibb, BMS, the Company, we, our or us in this 2022 Form 10-K, unless the context otherwise indicates. Throughout this 2022 Form 10-K, we have used terms which are defined below:
| 2022 Form 10-K | Annual Report on Form 10-K for the fiscal year ended December 31, 2022 | LIBOR | London Interbank Offered Rate | ||||||||
| 2021 Plan | 2021 Stock Award and Incentive Plan | Lilly | Eli Lilly and Company | ||||||||
| 2seventy bio | 2seventy bio, Inc. | LOE | loss of exclusivity | ||||||||
| 340B Program | 340B Drug Pricing Program | MAA | Marketing Authorization Application | ||||||||
| AbbVie | AbbVie Inc. | MCOs | Managed Care Organizations | ||||||||
| ACA | Patient Protection and Affordable Care Act | MDL | multi-district litigation | ||||||||
| Agenus | Agenus Inc. | MDS | myelodysplastic syndromes | ||||||||
| aGVHD | acute graft-versus-host disease | Mead Johnson | Mead Johnson Nutrition Company | ||||||||
| ALL | acute lymphoblastic leukemia | Merck | Merck & Co., Inc. | ||||||||
| Amgen | Amgen Inc. | MF | myelofibrosis | ||||||||
| Amylin | Amylin Pharmaceuticals, Inc. | MPM | Malignant Pleural Mesothelioma | ||||||||
| ANDA | abbreviated New Drug Application | MSI-H | high microsatellite instability | ||||||||
| AstraZeneca | AstraZeneca PLC | MyoKardia | MyoKardia, Inc. | ||||||||
| ASC | Accounting Standards Codification | NASH | Non alcoholic steatohepatitis | ||||||||
| BCMA | B-cell maturation antigen | NAV | net asset value | ||||||||
| Biogen | Biogen, Inc. | NDA | New Drug Application | ||||||||
| Biohaven | Biohaven Pharmaceutical Holding Company Ltd. | Nektar | Nektar Therapeutics | ||||||||
| BLA | Biologics License Application | NKT | natural killer T | ||||||||
| bluebird | bluebird bio, inc. | Nimbus | Nimbus Therapeutics, LLC | ||||||||
| BridgeBio | BridgeBio Pharma Inc. | Novartis | Novartis Pharmaceutical Corporation | ||||||||
| CAR-T | Chimeric Antigen Receptor T cells | NSCLC | non-small cell lung cancer | ||||||||
| Celgene | Celgene Corporation acquired by BMS on November 20, 2019 | NVAF | non-valvular atrial fibrillation | ||||||||
| CERCLA | U.S. Comprehensive Environmental Response, Compensation and Liability Act | OCE | Oncology Center of Excellence | ||||||||
| cGMP | current Good Manufacturing Practices | OECD | Organization for Economic Co-operation and Development | ||||||||
| Cheplapharm | Cheplapharm Arzneimittel GmbH | OIG | Office of Inspector General of the U.S. Department of Health and Human Services | ||||||||
| CML | chronic myeloid leukemia | Ono | Ono Pharmaceutical Co., Ltd. | ||||||||
| COSO | Committee of Sponsoring Organizations of the Treadway Commission | OTC | over-the-counter | ||||||||
| CRC | colorectal cancer | Otsuka | Otsuka Pharmaceutical Co., Ltd. | ||||||||
| DMC | Data Monitoring Committee | PBMs | Pharmacy Benefit Managers | ||||||||
| Dragonfly | Dragonfly Therapeutics, Inc. | PBRGs | People and Business Resource Groups | ||||||||
| DSA | Distribution Services Agreement | PCAOB | Public Company Accounting Oversight Board | ||||||||
| EC | European Commission | PD-1 | programmed death receptor-1 | ||||||||
| EGFR | estimated glomerular filtration rate | PDMA | Prescription Drug Marketing Act | ||||||||
| Eisai | Eisai Co., Ltd. | PDUFA | Prescription Drug User Fee Act | ||||||||
| ELA | excess loss account | Pfizer | Pfizer, Inc. | ||||||||
| EMA | European Medicines Agency | Prothena | Prothena Corporation | ||||||||
| EPO | European Patent Office | PhRMA Code | Pharmaceutical Research and Manufacturers of America’s Professional Practices Code | ||||||||
| EPS | earnings per share | PRP | potentially responsible party | ||||||||
| ESA | erythoropoiesis-stimulating agent | PsA | psoriatic arthritis | ||||||||
| ESCC | esophageal squamous cell carcinoma | PTR | patent term restoration | ||||||||
| Evotec | Evotec SE | R&D | research and development | ||||||||
| EU | except as otherwise noted, EU refers to the United Kingdom plus the countries that are members of the European Union | RA | rheumatoid arthritis | ||||||||
| FASB | Financial Accounting Standards Board | RCC | renal cell carcinoma | ||||||||
| FDA | U.S. Food and Drug Administration | RDP | Regulatory Data Protection | ||||||||
| FL | follicular lymphoma | REMS | Risk Evaluation and Mitigation Strategy | ||||||||
| GAAP | U.S. generally accepted accounting principles | Roche | Roche Holding AG | ||||||||
| Gilead | Gilead Sciences, Inc. | RS | ring sideroblast | ||||||||
| GILTI | global intangible low taxed income | Sanofi | Sanofi S.A. | ||||||||
| GlaxoSmithKline | GlaxoSmithKline PLC | sBLA | supplemental Biologics License Application | ||||||||
| GTN | gross-to-net | SEC | U.S. Securities and Exchange Commission | ||||||||
| Halozyme | Halozyme Therapeutics, Inc. | SLE | systemic lupus erythematosus | ||||||||
| HCC | hepatocellular carcinoma | SPC | Supplementary Protection Certificate | ||||||||
| HCM | hypertrophic cardiomyopathy | TCJA | the Tax Cuts and Jobs Act of 2017 | ||||||||
| HIV | human immunodeficiency virus | UC | ulcerative colitis | ||||||||
| Immatics | Immatics N.V. | U.S. | United States | ||||||||
| IO | immuno-oncology | UK | United Kingdom | ||||||||
| IPRD | in-process research and development | VAT | value added tax | ||||||||
| IRS | Internal Revenue Services | VTE | venous thromboembolic | ||||||||
| JIA | Juvenile Idiopathic Arthritis | WTO | World Trade Organization | ||||||||
EXHIBIT INDEX
The Exhibits listed below are identified by numbers corresponding to the Exhibit Table of Item 601 of Regulation S-K. The Exhibits designated by the symbol ‡‡ are management contracts or compensatory plans or arrangements required to be filed pursuant to Item 15. The symbol ‡ in the Page column indicates that the Exhibit has been previously filed with the Commission and is incorporated herein by reference. Unless otherwise indicated, all Exhibits are part of Commission File Number 1-1136.
| ‡‡10mm. | Bristol-Myers Squibb Company Non-Employee Directors’ Stock Option Plan, as amended (as approved by the Stockholders on May 2, 2000, incorporated herein by reference to Exhibit A to the 2000 Proxy Statement dated March 20, 2000). | ‡ | ||||||||||||
| ‡‡10nn. | Squibb Corporation Deferral Plan for Fees of Outside Directors, as amended (as adopted, incorporated herein by reference to Exhibit 10e Squibb Corporation 1991 Form 10-K for the fiscal year ended December 31, 1987, File No. 1-5514; as amended effective December 31, 1991 incorporated herein by reference to Exhibit 10m to the Form 10-K for the fiscal year ended December 31, 1992). | ‡ | ||||||||||||
| ‡‡10oo. | Bristol-Myers Squibb Company 2017 Stock Incentive Plan (incorporated herein by reference to Exhibit 99.1 to the registration statement on Form S-8 filed on November 25, 2019). | ‡ | ||||||||||||
| ‡‡10pp. | Bristol-Myers Squibb Company 2014 Equity Incentive Plan (incorporated herein by reference to Exhibit 99.2 to the registration statement on Form S-8 filed on November 25, 2019). | ‡ | ||||||||||||
| ‡‡10qq. | Bristol-Myers Squibb Company 2021 Stock Award and Incentive Plan (incorporated herein by reference to Exhibit B to Bristol Myers-Squibb Company’s Definitive Proxy Statement filed on March 25, 2021) | ‡ | ||||||||||||
| ‡‡10rr. | Letter Agreement between Bristol-Myers Squibb Company and Mr. David Elkins, dated as of May 30, 2019 (incorporated herein by reference to Exhibit 10iii to the Form 10-K for the fiscal year ended December 31, 2019). | ‡ | ||||||||||||
| 21. | Subsidiaries of the Registrant (filed herewith). | E-21-1 | ||||||||||||
| 23. | Consent of Deloitte & Touche LLP (filed herewith). | E-23-1 | ||||||||||||
| 31a. | Section 302 Certification Letter (filed herewith). | E-31-1 | ||||||||||||
| 31b. | Section 302 Certification Letter (filed herewith). | E-31-2 | ||||||||||||
| 32a. | Section 906 Certification Letter (filed herewith). | E-32-1 | ||||||||||||
| 32b. | Section 906 Certification Letter (filed herewith). | E-32-2 | ||||||||||||
| 101. | The following financial statements from the Bristol-Myers Squibb Company Annual Report on Form 10-K for the years ended December 31, 2022, 2021 and 2020, formatted in Inline Extensible Business Reporting Language (XBRL): (i) consolidated statements of earnings, (ii) consolidated statements of comprehensive (loss)/income, (iii) consolidated balance sheets, (iv) consolidated statements of cash flows, and (v) the notes to the consolidated financial statements. | |||||||||||||
| 104. | The cover page from the Company’s Annual Report on Form 10-K for the year ended December 31, 2022, formatted in Inline XBRL. |
| † | Confidential treatment has been granted for certain portions which are omitted in the copy of the exhibit electronically filed with the Commission. |
| * | Indicates, in this 2022 Form 10-K, brand names of products, which are registered trademarks not solely owned by the Company or its subsidiaries. Abilify is a trademark of Otsuka Pharmaceutical Co., Ltd.; Atripla is a trademark of Gilead Sciences, LLC; Byetta is a trademark of Amylin Pharmaceuticals, LLC; Cabometyx is a trademark of Exelixis, Inc.; Farxiga and Onglyza are trademarks of AstraZeneca AB; Gleevec is a trademark of Novartis AG; Keytruda is a trademark of Merck Sharp & Dohme Corp.; Otezla is a trademark of Amgen Inc.; Plavix is a trademark of Sanofi; Tecentriq is a trademark of Genentech, Inc.; and Yescarta is a trademark of Kite Pharma, Inc. Brand names of products that are in all italicized letters, without an asterisk, are registered trademarks of BMS and/or one of its subsidiaries. |
Previous: Item 15. EXHIBITS AND FINANCIAL STATEMENT SCHEDULE.